Transcranial alternating current stimulation of the sensorimotor system: towards customized protocols

Abstract The use of Transcranial Alternating Current Stimulation (tACS) on the motor system is growing fast. However, it as attractive full controversies due to variety reported effects. It may now be possible orchestrate brain oscillatory activity by stimulating trough external periodic electrical forces. mere advantage having specific frequency effects functions, has been obscured reasonable lack clear-cut evidence issues such amount time induce entrainment effects, offline versus online phase and individual differences age state. Here we review a series studies that break through and/ or consider issues, revealing tACS can an optimal tool for investigating sensorimotor with great potential in clinical application. Moreover, will show how test Magnetic (TMS) – combined approach. Throughout experiments, navigated stimulation used allow exact repositioning TMS coil within across experimental conditions. primary cortex induces frequency- state-dependent Online more effective rather than stimulation. Therefore, We transcranial are depending several factors have controlled electrodes montage, intensity, delivering sinusoidal amazing boost cortical excitability enhancement behavioral performance. research should step forward toward customized protocols replicable clear Acknowledgements: This work/article output project implemented part Basic Research Program at National University Higher School Economics (HSE University) Category Technology Methods Research: 8. Keywords: tACS, Motor cortex,